For this project, the degenerative effects of the glaucomatous E50K mutation in the Optineurin gene were characterized. The results were quantified and were compared to cells treated with a compound that improved neuronal length.

I synthesize polymeric nanoparticles that encapsulate the oncolytic and hydrophobic drug Paclitaxel, which can be delivered past the blood brain barrier via nanocarrier and shows promise in treating the brain cancer glioblastoma. We are currently usi ... ng MTT and methylene blue assays to test the nanoparticles in cell culture and determine cell viability, and we are planning on attaching the CD133 aptamer to the nanoparticles for targeted drug deliver. Read more

The goal of this project was to test the cytotoxicity of anti-cancer drugs when used in combination with hyperthermia. One compound I tested showed signs of high cytotoxicity to cancer cells which we could then start testing the drug on in vivo mice ... models. Read more

Working on Software improvements for a peer-led Augmented Reality app using Unity Software, Ultimaker program.

The goal of this project was to identify students' perceptions on the barriers and benefits of an online cross-cultural learning environment. Students from IU and Moi University in Kenya worked together for two years to complete this project.

The pandemic shut down a large portion of tourism worldwide, causing many issues in this industry. Preparedness for a similar situation through careful reflection on the coronavirus and what was effective and ineffective in bringing tourism back will ... make it easier to handle in case there is another pandemic in the future. Read more

The goal of this project was to conduct a systemic literature review to explore the therapeutic potential of senolytics in the treatment of diabetic retinopathy (DR). We discovered many senolytics that have the potential to elevate the progression of ... DR and they are slowly but surely advancing on to clinical trials. Read more

My internship site collected survey data from family medicine residencies in Indiana and various department ACs in the IU School of Medicine to create reports. These reports are used to help improve the programs for the school and state health progra ... ms as a whole. Read more

The goal of this research project was to determine the essentiality of a gene which is required for the malaria parasite Plasmodium Falciparum to replicate. Understanding the essential sequence that codes for this gene may reveal druggable targets fo ... r future antimalarial treatments. Read more

The goal of this project was to develop a survey to send to practicing US physicians about their needs, both met and unmet. From the results from both international and local graduates, new ideas and programs will be thought of to help best support t ... hem in their training. Read more